LOCALIZED BONE REGENERATION WITH PORCINE BONE: 18-YEAR FOLLOW-UP

L. Pagliani¹ , F. Cecchetti² , S. Volpe³ , L. Volpe³, P. Pagliani¹, M. Di Girolamo⁴

¹ Private Practice in Milan and Legnano, Italy
² Department of Social Dentistry and Gnathological Rehabilitation, National Institute for Health, Migration and Poverty (NIHMP), Rome, Italy
³ Private Practice, Rome, Italy
⁴ Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Rome, Italy

Correspondence to:

Annals of Stomatology 2025 May-August 5(2): Ahead of Print
https://doi.org/10.69129/stomatol/2025v5iss2_7

Received: 4 June 2025 Accepted: 30 July 2025

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Abstract

The presence of localised bone defects in the alveolar processes can prevent the use of implants, due to insufficient bone volume for osseointegration. Localised bone resorption can also prevent a good aesthetic result due to poor soft tissue support. Autologous bone grafting is considered the gold standard, but it has disadvantages for the patient, such as a donor site and the risk of morbidity. The use of alloplastic, allogenic, or xenogenic grafts has therefore become a very attractive alternative. A recent study conducted on the maxilla of rabbits has shown that porcine bone grafting exhibits strong osteoconductive properties and, over time, is remodelled and replaced with new bone. The aim of this study is to describe a technique designed to reconstruct a bone volume suitable for implant placement and, therefore, capable of supporting soft tissues in order to achieve an adequate aesthetic result with an 18-year follow-up of prosthetic loading. Bone augmentation was also evaluated from a histological point of view at the time of dental implant placement.

Keywords: bone regeneration, dental implants, porcine bone, xenogeneic grafts