ORAL MANIFESTATIONS IN PAGET’S DISEASE: A NARRATIVE REVIEW

F. Loffredo¹ , R.A. Assanti¹

¹ Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, Naples, Italy

Correspondence to:

Annals of Stomatology 2025 May-August 5(2): 87-91
https://doi.org/10.69129/stomatol/2025v5iss2_4

Received: 2 August 2025 Accepted: 29 August 2025

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Abstract

Paget’s disease (PD) is a bone disorder that can affect both single and multiple bones, leading to bone hypertrophy, cortical expansion, and a pathological bone structure that may predispose individuals to fractures. Paget’s disease is a complex disorder. Current evidence suggests that genetic factors are crucial in susceptibility, but it is not the only cause. Numerous studies have found a possible association between paramyxovirus exposure and the disease. Today, the role that the paramyxoviruses may play in this disease is still unclear, and the chance that earlier exposure to a viral infection early in life might play a part in PD cannot be totally excluded. This literature review highlights the most common aspects among patients with Paget’s disease, including jaw and dental alveoli deformation with possible loss of dental elements, pulp calcification, and the rare occurrence of mandible fractures.

Keywords: bone, disease fracture, Paget