MEIGE SYNDROME: A NARRATIVE REVIEW
G. Greco1* and P. Carls2
1 Dental School, University Milano Bicocca, Milano, Italy;
2 Consultant, Oral-Maxillofacial Surgeon, 69 Banbury Road, Oxford, UK.
*Correspondence to:
Gildo Greco, DDS,
Dental School,
University Milano Bicocca,
Milano, Italy.
e-mail: gildo.grecomail.com
ABSTRACT
A particular combination of oromandibular dystonia combined with blepharospasm is know as Meige’s syndrome. In order to avoid any misunderstandings, diagnosis is primarily clinical and necessitates a high index of suspicion. Striatal dopaminergic predominance is the most frequently accepted theory because the exact mechanism is unkown. Unfortunately, there is no cure, but injections of botulinum toxin and other medication classes, including anticholinergics, tetrabenazine, baclofen, and benzodiazepines, provide relief.
KEYWORDS: Meige syndrome, spasm, dystonia, eye, muscle
