MEDICAL OZONE TREATMENTS. THE GOOD, THE BAD, AND THE UGLY

M. de los Ángeles Erario¹ , Aníbal Martín Grangeat²

¹ Biochemist Researcher Argentinian Institute of Ozonetherapy, IAOT, Autonomous City of Buenos Aires, Argentina; Clinical Chemistry, Central Laboratory, Bernardino Rivadavia General Acute Hospital, CABA, Argentina
² Neurosurgeon, Medical Director of Argentinian Institute of Ozonetherapy, IAOT Autonomous City of Buenos Aires, Argentina

Correspondence to:

Annals of Stomatology 2025 May-August 5(2): Ahead of Print
https://doi.org/10.69149/orthopedics/2025v7iss2_8

Received: 3 June 2025 Accepted: 25 July 2025

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Abstract

Although medical ozone treatments are becoming increasingly frequent, there is still a lack of information regarding complications or adverse effects. Medical ozone is a valuable therapeutic resource when used appropriately and under the supervision of qualified doctors. It is essential that physicians utilize medical ozone within their respective medical specialties. We must abandon the notion that ozone has no adverse effects or complications. A few cases of complications related to ozone are described in the scientific literature index. Some papers deal with actual complications, but others are biased and misinformed. We have analyzed the most popular and controversial papers to reach a conclusion. It is time for the entire medical community to start sharing their experiences, including both successes and failures. This is the only way to advance and continue learning for ozone to be considered as the valuable therapeutic resource that it is.

Keywords: chronic inflammation, chronic oxidative stress, ozone, therapy